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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
13.03
Human Site:
S1099
Identified Species:
22.05
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S1099
P
G
Y
D
G
K
T
S
I
S
R
W
I
V
E
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S1054
P
G
Y
D
G
K
T
S
I
S
R
W
I
V
E
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
Y1038
T
L
Q
F
R
P
G
Y
D
G
K
T
S
I
S
Dog
Lupus familis
XP_547004
2144
235913
E1057
E
E
W
V
S
L
Y
E
E
E
N
E
P
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
A1081
P
G
Y
D
G
K
T
A
I
C
R
W
I
V
E
Rat
Rattus norvegicus
XP_001073292
2181
239558
A1069
P
G
Y
D
G
K
T
A
I
C
R
W
I
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
L1054
Q
M
L
E
I
P
N
L
T
P
Y
T
H
Y
R
Chicken
Gallus gallus
Q8AV58
2169
239459
K1054
D
G
K
T
S
I
C
K
W
I
V
E
G
Q
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
T1050
M
L
E
V
P
N
L
T
P
F
T
H
Y
R
F
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
M201
I
R
L
S
D
R
V
M
V
G
K
D
G
N
L
Fruit Fly
Dros. melanogaster
O97394
2224
246236
S1096
P
G
F
D
G
N
S
S
I
T
K
W
K
V
E
Honey Bee
Apis mellifera
XP_623565
2176
242722
S1060
P
G
F
D
G
N
S
S
I
I
K
W
T
V
Q
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
A1086
P
G
F
D
G
H
T
A
I
R
Q
W
V
V
E
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
P1395
P
G
N
N
G
N
S
P
L
R
Y
Y
I
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
100
0
0
N.A.
86.6
86.6
N.A.
0
6.6
N.A.
0
0
60
53.3
60
26.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
93.3
93.3
N.A.
6.6
6.6
N.A.
6.6
20
86.6
80
86.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
15
0
0
0
0
0
% C
% Asp:
8
0
0
50
8
0
0
0
8
0
0
8
0
8
8
% D
% Glu:
8
8
8
8
0
0
0
8
8
8
0
15
0
0
43
% E
% Phe:
0
0
22
8
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
65
0
0
58
0
8
0
0
15
0
0
15
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
0
% H
% Ile:
8
0
0
0
8
8
0
0
50
15
0
0
36
15
0
% I
% Lys:
0
0
8
0
0
29
0
8
0
0
29
0
8
0
0
% K
% Leu:
0
15
15
0
0
8
8
8
8
0
0
0
0
0
8
% L
% Met:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
29
8
0
0
0
8
0
0
8
0
% N
% Pro:
58
0
0
0
8
15
0
8
8
8
0
0
8
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
8
0
0
8
8
% Q
% Arg:
0
8
0
0
8
8
0
0
0
15
29
0
0
8
8
% R
% Ser:
0
0
0
8
15
0
22
29
0
15
0
0
8
0
8
% S
% Thr:
8
0
0
8
0
0
36
8
8
8
8
15
8
0
0
% T
% Val:
0
0
0
15
0
0
8
0
8
0
8
0
8
50
8
% V
% Trp:
0
0
8
0
0
0
0
0
8
0
0
50
0
0
0
% W
% Tyr:
0
0
29
0
0
0
8
8
0
0
15
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _